Table 1. Metabolic differences between ATP10D deficient and transgenic mice on high fat diet.
| CTRL | SD | TG | SD | p value | |
| Metabolic Parameters—Plasma | |||||
| Glucose [mmol/L] | 7.9 | 0.9 | 4.9 | 1.1 | 0.031 |
| Insulin [ng/mL] | 3.6 | 0.5 | 1.1 | 0.5 | 0.012 |
| TAG [mg/dL] | 128.4 | 13.4 | 94.6 | 8.7 | 0.042 |
| FFA [mmol/L] | 1.0 | 0.1 | 1.0 | 0.2 | 0.084 |
| Cholesterol [mg/dL] | 94.6 | 8.5 | 83.9 | 7.9 | 0.085 |
| Hepatic TAG and FFA [ng/μg tissue] | |||||
| CTRL | SD | TG | SD | p value | |
| FFA | 5.6 | 0.3 | 4.4 | 0.3 | 0.001 |
| TAG | 174.7 | 37.6 | 255.8 | 48.0 | 0.019 |
| Hepatic and plasma d18:1/16:0 + d18:1/24:1 hexosylceramide | |||||
| CTRL | SD | TG | SD | p value | |
| Plasma [μmol/L] | 0.77 | 0.15 | 0.34 | 0.04 | 0.002 |
| Liver [pmol/mg] | 8.20 | 0.94 | 4.08 | 0.64 | 0.00008 |
| Metabolic Parameters—Others | |||||
| CTRL | SD | TG | SD | p value | |
| VO2 [L/kg/h] | 4537 | 189 | 5028 | 165 | 0.024 |
| VCO2 [L/kg/h] | 3164 | 102 | 3522 | 89 | 0.021 |
| RER | 0.9 | 0.1 | 0.9 | 0.1 | 0.523 |
| Movement [AU] | 4855 | 946 | 4912 | 938 | 0.834 |
Significant differences between both groups are shown in bold and italics. CTRL, ATP10D deficient; SD, standard deviation; TG, ATP10D transgenic; TAG, triacylglycerols; FFA, free fatty acids; VO2, O2 consumption; VCO2, CO2 production; RER, respiratory exchange ratio, AU, arbitrary units. n = 5.