EMP2 is expressed in trophoblast layers throughout gestation. (A) Uteri or placentas were collected from wild type (Emp2+/+) mice following mating to wild type (Emp2+/+) males at E6.5, E9.5, E12.5, and E16.5 and stained for EMP2 expression. Left, Magnification=40×. Insets are provided below for E6.5 (B), E9.5 (C), E12.5 (D), and E16.5 (E). Magnification, 100×. Em, embryo; En, endometrium; AM, amnion; Ch, chorion; Dec, decidua; EPC, ectoplacental cone; GC, giant cells; JZ, Junctional zone; LZ, labyrinth zone; Pre-gc, glycogen cells; TE, trophectoderm; SP, spongiotrophoblast.