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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Hepatology. 2017 Apr 28;65(6):2005–2018. doi: 10.1002/hep.29076

Figure 3. Effect of JTE-013 on TCA- and S1P-induced cell invasion in MLE Cells.

Figure 3

MLE cells were plated in the upper transwell inserts. Cells were pretreated with JTE-013 (10 μM) for 30min then treated with TCA (100 μM) or S1P (100 nM) or vehicle control (DMSO) for 24h. At the end of treatment, the number of invasion cells on the lower surface of inserts and the invasion index were analyzed as described in Methods. (A) Representative images for each treatment are shown. (B) Invasion index. *p<0.05 compared to vehicle control; #p<0.05, ##p<0.01 compared to the same treatment group without JTE-013; n=3.