Table 1.
Characteristics | Total Transplanted (N=106) |
---|---|
| |
Demographics | |
| |
Age (year) | |
Mean ± SD | 11.9 ± 6.20 |
| |
Male Gender | 70 (66.0) |
| |
| |
Race | |
| |
White | 77 (72.6) |
| |
Black or African American | 14 (13.2) |
| |
Asian | 8 (7.5) |
| |
Other | 2 (1.9) |
| |
Unknown or Not Reported | 5 (4.7) |
| |
| |
Ethnicity | |
| |
Hispanic or Latino | 47 (44.3) |
| |
Not Hispanic or Latino | 53 (50.0) |
| |
Unknown or Not Reported | 6 (5.7) |
| |
| |
Height and Weight | |
| |
Height Z scores | |
| |
Mean ± SD | −1.2 ± 1.70 |
| |
| |
Weight Z scores | |
| |
Mean ± SD | −0.5 ± 1.55 |
| |
| |
| |
BMI Z scores | |
| |
Mean ± SD | −0.2 ± 4.19 |
| |
| |
Use of Induction Therapy | |
| |
Basiliximab | 36 (34.0) |
| |
Daclizumab | 45 (42.5) |
| |
Thymoglobulin | 27 (25.5) |
| |
| |
Use of Maintenance Therapy | |
| |
Tacrolimus | 105 (99.1) |
| |
MMF | 104 (98.1) |
| |
Prednisone | 63 (59.4) |
| |
Sirolimus | 20 (18.9) |
| |
Azathioprine | 7 (6.6) |
| |
Cyclosporine | 2 (1.9) |
| |
Leflunomide | 1 (0.9) |
| |
| |
Clinical Infection | |
| |
Bacterial | 22 (20.8) |
| |
Fungal | 3 (2.8) |
| |
Viral | 27 (25.5) |
| |
| |
Protozoal | 2 (1.9) |
| |
Parasitic | 1 (0.9) |
| |
| |
Viremia by PCR | |
| |
| |
CMV+ by Local or Central PCR | 24 (22.6) |
| |
EBV+ by Local or Central PCR | 36 (34.0) |
| |
BKV+ by Local or Central PCR | 24 (22.6) |
| |
Other+ by Central PCR [1] | 39 (36.8) |
| |
| |
Clinical Outcomes | |
| |
Alloimmune Failure | 40 (37.7) |
| |
BPAR incl Borderline | 24 (22.6) |
| |
denovo DSA | 23 (21.7) |
| |
Viremia | 77 (72.6) |
| |
|
Other viruses include adeno, HHV, and JCV.