Table 1.
Gene | SNP | Sample size (case/control) | MAF (cases/control) | Allelic P | Genotypic P | Reference/publication |
---|---|---|---|---|---|---|
COMT | rs362204 | 215/215 | 0.34/0.27 | 0.028 | Srivastava et al., 2010 | |
TH | rs6356 | 0.44/0.47 | 0.04 | Srivastava et al., 2010 | ||
DBH | rs1108580 | 0.34/0.33 | 0.025 | Srivastava et al., 2010 | ||
COMT | rs4680 | 398/241 | 0.026 | 0.017 (dominant model) | Gupta et al., 2009a | |
DRD2 | rs11608185 | 254/225 | 0.043 | Gupta et al., 2009b | ||
DRD2 | rs6275 | 0.011 | Gupta et al., 2009b | |||
COMT | rs4680 | 0.029 | 0.035 | Gupta et al., 2009b | ||
GRIK3 | T928G (Ser310Ala) | 100/100 | 0.44/0.31 | 0.01 | <0.000001 | Ahmad et al., 2009 |
SLC6A4 | rs2066713 | 243/243 | 0.31/0.44 | <0.001 | <0.001 | Vijayan et al., 2009 |
5HTTLPR | 0.42/0.5 | 0.008 | 0.03 | Vijayan et al., 2009 | ||
STin2 polymorphisms | 0.28/0.39 | 0.001 | 0.002 | Vijayan et al., 2009 | ||
Leptin gene | rs 4731426 | 154 cases for weight gain | median weight gain | 0.05 | Srivastava et al., 2008 | |
extreme weight gain | 0.019 | Srivastava et al., 2008 | ||||
DRD2(H313HTT) | rs 6275 | 213/196 | 0.43/0.49 | 0.004 | Vijayan et al., 2007 | |
DRD2(H313HTT) | rs 6275 | 101/145 | 0.0012 | Kukreti et al., 2006 | ||
DRD3 | rs10934254 | 0.03 | Talkowski et al., 2006 | |||
SYNGR1 | rs909685 | 193/107 | 0.53/0.42 | 0.01 | 0.03 | Verma et al., 2005a |
rs715505 | 0.45/0.29 | 0.00007 | 0.0004 | Verma et al., 2005a | ||
rs6001566 | 0.17/0.24 | 0.03 | 0.10 | Verma et al., 2005a | ||
MLC1 | rs2235349 | 193/116 | Verma et al., 2005b | |||
MLC1 | rs2076137 | 193/116 | Verma et al., 2005b | |||
NOTCH 4 | 197/198(GAAG) 54 | 182 trios | 0.014 | Prasad et al., 2004 | ||
NOTCH 4 | (CTG)6 | 182 trios | 0.02 | Prasad et al., 2004 | ||
HTR2A (promoter) | 436/700 | 0.41/0.47 | 0.001 | Semwal et al., 2002 | ||
TPH (gene) | 293/440 | 0.34/0.46 | 0.001 | Semwal et al., 2002 | ||
Ch 22 CAG repeat | 22CH3 | 108/129 | <0.02 | Saleem et al., 2001 |
SNP: single nucleotide polymorphism; MAF-minor allele frequency.