Table 2.
Effects of SLAB51 on KEGG orthologs in 24 weeks old wt and 3xTg-AD mice.
| KEGG orthologs | LDA score | Group |
|---|---|---|
| Two-component system | 4.20 | 3xTg-AD not treated |
| Bacterial motility proteins | 4.13 | 3xTg-AD not treated |
| Secretion system | 4.10 | 3xTg-AD not treated |
| General function prediction only | 4.55 | 3xTg-AD treated SLAB51 |
| DNA repair and recombination proteins | 4.47 | 3xTg-AD treated SLAB51 |
| Pyrimidine metabolism | 4.31 | 3xTg-AD treated SLAB51 |
| Peptidases | 4.30 | 3xTg-AD treated SLAB51 |
| Chromosome | 4.21 | 3xTg-AD treated SLAB51 |
| Amino sugar and nucleotide sugar metabolism | 4.17 | 3xTg-AD treated SLAB51 |
| Ribosome biogenesis | 4.15 | 3xTg-AD treated SLAB51 |
| Methane metabolism | 4.14 | 3xTg-AD treated SLAB51 |
| DNA replication proteins | 4.13 | 3xTg-AD treated SLAB51 |
| Alanine aspartate and glutamate metabolism | 4.06 | 3xTg-AD treated SLAB51 |
| Energy metabolism | 4.04 | 3xTg-AD treated SLAB51 |
| Glycolysis-gluconeogenesis | 4.02 | 3xTg-AD treated SLAB51 |
| Transcription machinery | 4.01 | 3xTg-AD treated SLAB51 |
| Homologous recombination | 4.01 | 3xTg-AD treated SLAB51 |
| Function unknown | 4.13 | wt not treated |
| Other ion-coupled transporters | 4.07 | wt treated SLAB51 |