Table 1.
Cardiac remodeling during more than 20 years of follow-up.
| Parameter | At baseline | At follow-up | p-value |
|---|---|---|---|
| LVIDD, mm | |||
| -All study subjects | 51.6 ± 4.9 | 51.9 ± 6.4 | 0.13 |
| -Controls | 51.3 ± 4.8 | 51.5 ± 6.6 | 0.68 |
| -Hypertension | 51.9 ± 5.0 | 52.5 ± 6.1 | 0.08 |
| IVS, mm | |||
| -All study subjects | 10.6 ± 2.2 | 10.7 ± 2.3 | 0.60 |
| -Controls | 10.1 ± 1.9 | 10.4 ± 2.7 | 0.039 |
| -Hypertension | 11.3 ± 2.2*** | 11.0 ± 1.8** | 0.049 |
| LVPW, mm | |||
| -All study subjects | 10.0 ± 1.8 | 10.6 ± 1.7 | < 0.001 |
| -Controls | 9.5 ± 1.8 | 10.3 ± 1.6 | < 0.001 |
| -Hypertension | 10.6 ± 1.8*** | 10.9 ± 1.8*** | 0.004 |
| LVMI, g/m2 | |||
| -All study subjects | 106.5 ± 27.1 | 114.6 ± 29.1 | < 0.001 |
| -Controls | 100.8 ± 24.7 | 110.1 ± 28.8 | < 0.001 |
| -Hypertension | 113.3 ± 28.3*** | 120.0 ± 28.5*** | 0.001 |
| FS, % | |||
| -All study subjects | 35.0 ± 5.7 | 38.4 ± 7.2 | < 0.001 |
| -Controls | 34.4 ± 5.7 | 38.8 ± 7.1 | < 0.001 |
| -Hypertension | 35.8 ± 5.5** | 37.9 ± 7.3 | < 0.001 |
| LAD, mm | |||
| -All study subjects | 38.8 ± 5.2 | 39.4 ± 6.7 | 0.028 |
| -Controls | 37.6 ± 5.0 | 38.2 ± 6.9 | 0.11 |
| -Hypertension | 40.3 ± 5.2*** | 40.9 ± 6.2*** | 0.14 |
The values are presented as mean ± SD. All study subjects: n = 552; controls: n = 295; hypertension (subjects with hypertension): n = 257. FS, fractional shortening; IVS, interventricular septum; LAD, left atrial diameter; LVIDD, left ventricular internal diastolic diameter; LVMI, left ventricular mass index; LVPW, left ventricular posterior wall.
***
p < 0.001,
**
p < 0.01 between controls and the subjects with hypertension.