Figure 4.

Comparison of dice coefficient between ROIs from gamma mixture components and lesion/NAWM masks in (left) RRMS and (right) SPMS groups. (Top) Comparison between lesion mask and ROI[m₁], and lesion mask and ROI[m₂] in (left) RRMS and (right) SPMS groups. The difference was shown to be significant in both RRMS (p < 0.00001) and SPMS (p < 0.00001) groups. (Bottom) Comparison between NAWM mask and ROI[m₁], and NAWM mask and ROI[m₂] in (left) RRMS and (right) SPMS groups. The difference was shown to be significant in both RRMS (p < 0.00001) and SPMS (p < 0.00001) groups. *p < 0.01, **p < 0.001, ***p < 0.0001, ****p < 0.00001.