Table 1. Baseline characteristics of all patients and between groups.
All patients (n = 225) | AAC (+) (n = 127) | AAC (–) (n = 98) | p-value | |
Age (years) | 72 ± 26 | 81 ± 29 | 61 ± 14 | < 0.001 |
Male | 169 (75) | 90 (71) | 77 (79) | 0.17 |
Weight (kg) | 66 ± 14 | 62 ± 11 | 72 ± 14 | < 0.001 |
BMI (kg/m2) | 24.6 ± 4.4 | 23.7 ± 3.9 | 26.3 ± 4.7 | < 0.001 |
Waist (cm) | 90 ± 11 | 87 ± 11 | 95 ± 10 | 0.002 |
SBP (mmHg) | 134 ± 32 | 131 ± 34 | 138 ± 29 | 0.08 |
DBP (mmHg) | 76 ± 19 | 72 ± 19 | 81 ± 17 | < 0.001 |
HR (1/min) | 85 ± 21 | 85 ± 22 | 85 ± 19 | 0.87 |
Active smoker | 47 (21) | 24 (19) | 23 (24) | 0.64 |
Hypertension | 153 (68) | 94 (74) | 58 (60) | 0.03 |
Diabetes | 99 (44) | 59 (47) | 39 (40) | 0.32 |
Prior MI | 38 (17) | 19 (15) | 18 (19) | 0.41 |
Prior PTCA | 47 (21) | 26 (21) | 19 (20) | 0.77 |
Prior CHF | 20 (9) | 14 (11) | 6 (6) | 0.19 |
Prior PAOD | 13 (6) | 11 (9) | 2 (2) | 0.03 |
BUN (mg/dl) | 33 ± 24 | 37 ± 24 | 27 ± 23 | 0.004 |
Cr (mg/dl) | 2.0 ± 2.1 | 2.4 ± 2.3 | 1.6 ± 1.7 | 0.004 |
Uric acid (mg/dl) | 7.2 ± 2.5 | 7.6 ± 2.9 | 6.5 ± 1.6 | 0.01 |
Total cholesterol (mg/dl) | 153 ± 39 | 148 ± 40 | 160 ± 37 | 0.02 |
HDL (mg/dl) | 37 ± 12 | 37 ± 14 | 37 ± 9 | 0.72 |
LDL (mg/dl) | 96 ± 35 | 92 ± 35 | 101 ± 37 | 0.11 |
TG (mg/dl) | 123 ± 70 | 110 ± 60 | 139 ± 77 | 0.003 |
Fasting blood glucose (mg/dl) | 152 ± 66 | 153 ± 73 | 151 ± 56 | 0.86 |
Medications | ||||
Aspirin | 63 (28) | 33 (26) | 29 (30) | 0.51 |
Clopidogrel | 36 (16) | 20 (16) | 16 (17) | 0.83 |
ACEI | 29 (13) | 16 (13) | 11 (12) | 0.73 |
ARB | 52 (23) | 32 (25) | 21 (21) | 0.53 |
BB | 52 (23) | 24 (19) | 27 (28) | 0.13 |
CCB | 45 (20) | 35 (28) | 10 (11) | 0.002 |
Nitrates | 36 (16) | 23 (18) | 12 (13) | 0.32 |
Statin | 47 (21) | 21 (17) | 26 (27) | 0.08 |
Data are represented as mean ± standard deviation or n (%).
AAC, aortic arch calcification; ACEI, angiotensinogen-converting enzyme inhibitor; ARB, angiotensin receptor blocker; BB, beta-adrenergic blocker; BMI, body mass index; BUN, blood urea nitrogen; CCB, calcium channel blocker; CHF, congestive heart failure; Cr, creatinine; DBP, diastolic blood pressure; HDL, high density lipoprotein; HR, heart rate; LDL, low density lipoprotein; MI, myocardial infarction; PAOD, peripheral arterial obstructive disease; PTCA, percutaneous coronary angioplasty; SBP, systolic blood pressure; TG, triglyceride.