Table 3.

Multivariate Cox regression model adjusted for possible predictors estimating cancer-specific and overall survival in 244 patients treated with cyto-reductive nephrectomy for metastatic renal cell carcinoma

	Cancer-specific survival			Overall survival
	HR	95% CI of HR	p value	HR	95% CI of HR	p value
Age	1.002	0.983–1.021	0.865	1.003	0.986–1.021	0.713
BMI (kg/m 2)	Reference (< 20)			Reference (< 20)
20–25	0.792	0.459–1.369	0.404	0.805	0.485–1.336	0.402
≥ 25	0.443	0.202–0.924	0.030	0.466	0.232–0.936	0.032
Albumin (g/dL)	Reference (< 3.5)			Reference (< 3.5)
3.5–4.3	0.776	0.440–1.370	0.382	0.716	0.426–1.204	0.208
≥ 4.3	0.784	0.399–1.544	0.482	0.713	0.383–1.328	0.287
Heng’s criteria	Reference (Low risk)			Reference (Low risk)
Intermediate risk	1.095	0.623–1.926	0.752	1.033	0.619–1.725	0.902
High risk	1.185	0.550–2.553	0.664	1.132	0.565–2.270	0.727
Cholesterol level (cat.)	2.162	1.221–3.829	0.008	2.013	1.206–3.361	0.007
Age	1.002	0.983–1.021	0.830	1.003	0.986–1.021	0.701
BMI (kg/m 2)	Reference (< 20)			Reference (< 20)
20–25	0.827	0.479–1.430	0.497	0.857	0.517–1.420	0.549
≥ 25	0.462	0.214–0.997	0.049	0.503	0.249–1.017	0.056
Albumin (g/dL)	Reference (< 3.5)			Reference (< 3.5)
3.5–4.3	0.882	0.498–1.561	0.665	0.789	0.468–1.327	0.371
≥ 4.3	0.892	0.437–1.821	0.753	0.769	0.401–1.473	0.428
Heng’s criteria	Reference (Low risk)			Reference (Low risk)
Intermediate	1.060	0.601–1.870	0.840	1.024	0.613–1.712	0.927
High risk	1.235	0.576–2.649	0.588	1.193	0.596–2.389	0.618
Cholesterol level (con.)	0.993	0.987–0.999	0.032	0.995	0.989–1.000	0.063

HR hazard ratio, CI confidence interval, BMI body mass index, con. Continuous variable, cat. Categorical variable