Table 2.

Effects of intravesical disulfide and all-thiol HMGB1 on mouse bladder histology

	Inflammation		Edema
Dose (μg)	ds HMGB1	all-thiol HMGB1	ds HMGB1	all-thiol HMGB1
0	0	0	0	0
1	0	0	0.4 ± 0.2	1.3 ± 0.7
2	0	0	0.7 ± 0.7	0.7 ± 0.3
5	0	0	0	1.0 ± 0.6
10	0	0	0.2 ± 0.2	0.9 ± 0.5
20	0.3 ± 0.3	0.3 ± 0.3	1.0 ± 1.0	0.7 ± 0.7

0 = vehicle control