Figure 1. Diverse Genetic Factors Converge on a Conserved Regulator.
The primary sex determination mechanisms are shown, from left to right, for Drosophila, Caenorhabditis, the box turtle Terrapene carolina, and humans. These proximate signals are then relayed by diverse signal transduction pathways that ultimately converge on a DM-family gene. The left image is from Muller [23]; the center-left image appears courtesy of Dr. Barbara Conradt, the center-right image appears courtesy of J.D. Willson, and the right image is from a plaque mounted on the NASA spacecraft Pioneer 11.
