Fig. 4.

The distributions of the average consecutive length of rate-limiting steps in the experiments with a calculated fixation probability for each mutation and a fluctuating population size are shown. The schemes of fluctuating experiments K1 (green), K2 (red), K3 (blue), K4 (yellow), and K5 (purple) are shown. Black bars correspond to the control experiments with population sizes 100 (C_K100), 10,000 (C_K10000), 1,000,000 (C_K1M).). Nominal p-values were obtained via permutation tests with the null hypothesis that the average absolute deviation in the number of consecutive generations for each step was zero