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. 2017 Apr 26;105(6):1259–1271. doi: 10.3945/ajcn.117.152546

FIGURE 2.

FIGURE 2

Path diagram of a single mediator model, where the product of the a and b coefficients defines the indirect effect of X on Y through M. The c′ coefficient denotes the direct effect of X on Y, controlling for M. In linear models with continuous outcomes, an estimate of the total effect of X on Y is parameterized as follows: c = ab + c′.