Fig. (2).

Effects of chronic RF-EMF in the expressions of APP, CTFs and Aβ-degrading enzymes in WT and Tg-5xFAD mice brain. A. Western blotting of FL-APP and CTFs of APP in the hippocampus and cortex extract in Tg-5xFAD and WT mice following RF-EMF exposure. The graph showed quantification of expression of APP and CTFs using band intensity of Tg-5xFAD mice. Values are presented as the mean ± SEM (n=3) and analyzed by two-tailed t-test (* p < 0.05 Tg-5xFAD (RF-) vs. Tg-5xFAD-RF (+)). B. A RT-PCR for Aβ-degrading enzymes genes, including NEP and IDE, performed using hippocampus and cortex tissues from WT and Tg-5xFAD mice with or without RF-EMF exposure. Values are presented as the mean ± SEM (n=3) and analyzed by ANOVA (analysis of variance) and Bonferroni post-hoc test.