Table 4.
Effect of ACE genotype on Outcomes in Caucasian Infants
ACE Genotype | ||||
II (n = 11) | ID (n = 17) | DD (n = 19) | P value | |
Oxygen at 28 days | 6/11 (55) | 10/15 (67) | 9/18 (47) | 0.620 |
Oxygen at 36 weeks PCA | 3/10 (30) | 4/15 (27) | 3/18 (17) | 0.674 |
Death <28 days | 0 (0) | 1 (16) | 1 (5) | 0.724 |
Death or Oxygen at 36 weeks | 4 (36) | 6 (35) | 4 (21) | 0.558 |
Death ≥ 28 days | 3 (27) | 1 (6) | 0 (0) | 0.039 |
IVHa | 2/10 (20) | 6/17 (35) | 1/19 (5) | 0.076 |
IVH ≥ Grade 3a | 2/10 (20) | 3/17 (18) | 1/19 (5) | 0.415 |
PVLa | 3/10 (30) | 0/17 (0) | 1/19 (5) | 0.022 |
Numbers in parenthesis represent percentages.
aNot all infants had cranial US evaluations
PCA Postconceptional age IVH Intraventricular Hemorrhage PVL Periventricular leukomalacia