. Author manuscript; available in PMC: 2018 Mar 15.

Published in final edited form as: Arch Biochem Biophys. 2017 Feb 11;618:32–43. doi: 10.1016/j.abb.2017.02.001

Table 1.

ACSL enzymes in INS-1 832/13 pancreatic beta cells prefer the unsaturated fatty acid arachidonate over the saturated fatty acid palmitate as a substrate. In human pancreatic islets that are composed of beta and non-beta cells, the fatty acid preferences are approximately equal.

	ACSL Enzyme Activity (nmol product formed/min/mg protein) Enzyme Substrate		Activity Ratio Arachidonate/Palmitate (mean ± SE)
	Arachidonate	Palmitate	Activity Ratio Arachidonate/Palmitate (mean ± SE)
INS-1 832/13 Cells	5.05 ± 0.32 (12)	2.76 ± 0.26 (12)	1.8 ± 0.04 (12)
Human Islets	2.08 ± 0.29 (3)	2.46 ± 0.52 (3)	0.84 ± 0.06 (3)