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. 2017 Feb 15;13(5):955–966. doi: 10.1080/15548627.2017.1287652

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Figure 3. — Atg5 disruption does not benefit MA9-AML mice survival. (A) Illustration of transplantation strategy: 1 million leukemia cells together with 0.25 million supporting cells were transplanted into BoyJ recipient mice after lethal irradiation. Intraperitoneal injection of polyI:C (plpC) was started 20 d post transplantation at the dosage of 100 μg/g, every other day for 4 injections. (B) Kaplan-Meier survival curve for the primary transplantation (n = 7 in Atg5^f/f group, n = 8 in Atg5^f/fMxCre group). (C) Kaplan-Meier survival curve for the secondary transplantation (n = 6 in Atg5^f/f group, n = 5 in Atg5^f/fMxCre group).