Skip to main content
. 2005 Jan 20;115(2):428–433. doi: 10.1172/JCI23269

Figure 5.

Figure 5

Repeated-measures ANOVA on data derived from 23 neuritic plaques imaged from 10 different untreated PDAPP;YFP transgenic mice and 18 plaques imaged from 7 different 10D5-treated PDAPP;Thy-1:YFP transgenic mice. All dystrophic neurites were imaged on day 0 and then reimaged on day 3. A significant treatment × day interaction for both the mean number [F1,28 = 25.092, P = 0.00003] of dystrophic neurites (A) and the mean total cross-sectional area [F1,28 = 21.037, P = 0.00009] of dystrophic neurites (B) was seen. In the absence of treatment, dystrophic neurites did not undergo significant changes in regard to number or cross-sectional area over a 72-hour period. However, a significant decrease in both mean number and mean cross-sectional area was seen in animals receiving 10D5 treatment. *P < 0.00005 versus untreated group.