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. Author manuscript; available in PMC: 2017 May 26.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2017 Jan 5;75:45–53. doi: 10.1016/j.pnpbp.2017.01.001

Table 2.

Summary of results from random-effects meta-analysis for all cognitive subdomains across all drug doses studied.

Cognitive subdomain Effect size (95% CI) I2 (p-value) Number of studies included
Overall cognitive index −0.057 (−0.16, 0.044) 0 (0.72) 13
Attention −0.077 (−0.20, 0.047) 0 (0.65) 14
Working memory −0.011 (−0.14, 0.12) 3 (0.42) 14
Executive function 0.006 (−0.18, 0.19) 32 (0.16) 9
Speed of processing −0.015 (−0.14, 0.11) 0 (0.98) 13
Verbal learning −0.076 (−0.25, 0.096) 16 (0.30) 9
Visual learning −0.048 (−0.19, 0.092) 0 (0.57) 11
Social cognition 0.031 (−0.15, 0.21) 0 (0.95) 5
Language 0.12 (−0.49, 0.72) 0 (0.38) 2

Note: negative effect size favors drug.