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. 2017 May 26;12(5):e0177568. doi: 10.1371/journal.pone.0177568

Table 1. Pharmacokinetic variables (mean, standard deviation, n = 34) for florfenicol.

Variable Units Mean SD
Cmax mg/L 3.04 1.82
AUC h*mg/L 53.7 9.32
AUMC h*h*mg/L 650 282
Tmax h 1.94 0.87
Cl/F L/h/kg 0.23 0.04
T1/2 h 11.0 9.02

Pharmacokinetic variables determined by non-compartmental analysis for florfenicol administered intramuscularly at a dose rate of 15mg/kg; data for two bioequivalent products (Nuflor and Norfenicol). Cmax = maximum concentration; AUC = area under plasma concentration-time curve; AUMC = area under the first moment curve; Tmax = time to reach maximum concentration; Cl/F = drug clearance scaled by bioavailability; T1/2 = terminal half-life. Values are geometric means except for Tmax (arithmetic mean) and T1/2 (harmonic mean).