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| Predicted daily doses (mg/kg) |
Target Attainment Rate | ||
|---|---|---|---|
| 50% | 90% | ||
| P. multocida | Bacteriostatic | 4.23 | 6.22 |
| Bactericidal | 6.50 | 9.58 | |
| 4 log10 reduction | 7.66 | 11.3 | |
| A. pleuropneumoniae | Bacteriostatic | 10.9 | 18.2 |
| Bactericidal | 21.1 | 35.2 | |
| 4 log10 reduction | 28.8 | 48.0 | |
Monte Carlo simulations to achieve 50 and 90% target attainment rate dosages at steady state for three levels of bacterial kill.
