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. 2017 May 26;12(5):e0177745. doi: 10.1371/journal.pone.0177745

Table 3. Incidence and adjusted hazard ratio of colorectal cancer stratified by different entities of inflammatory bowel disease patients with or without cholecystectomy.

Cholecystectomy
No Yes
Variables N No. of Events PY Rate# N No. of Events PY Rate# Crude HR Adjusted HR
(95%CI) (95%CI) †
Ulcerative colitis 234 2 1897 1.05 214 6 1533 3.91 3.53 2.78
(0.71, 17.4) (0.54, 14.3)
Crohn’s disease 291 4 2349 1.7 311 1 2473 0.4 0.24 0.13
(0.03, 2.18) (0.01, 1.49)

Rate#, incidence rate, per 1000 person-years; Crude HR, relative hazard ratio

Adjusted HR†: multivariable analysis including age, sex, and comorbidities