Table 4. Incidence of colorectal cancer location using Cox model measured hazards ratio by type of cholecystectomy.
Variables(ICD-9 code) | Event | Rate# | Crude HR* | Adjusted HR† (95% CI) |
---|---|---|---|---|
(95% CI) | ||||
Colon cancer | ||||
Non-cholecystectomycohort (N = 525) | 6 | 1.41 | 1(Reference) | 1(Reference) |
Cholecystectomy | ||||
Lapraroscopic cholecystectomy (N = 282) | 2 | 0.88 | 0.62(0.13, 3.07) | 0.44(0.09, 2.22) |
Non-lapraroscopic cholecystectomy (N = 243) | 5 | 2.9 | 2.06(0.63, 6.76) | 1.11(0.32, 3.78) |
Colon cancer (except rectum) (ICD-9 153) | ||||
Non-cholecystectomycohort (N = 525) | 3 | 0.71 | 1(Reference) | 1(Reference) |
Cholecystectomy | ||||
Lapraroscopic cholecystectomy (N = 282) | 1 | 0.44 | 0.62(0.07, 5.99) | 0.40(0.04, 3.92) |
Non-lapraroscopic cholecystectomy (N = 243) | 5 | 2.9 | 4.21(1.01, 17.6)* | 2.81(0.63, 12.5) |
Rectal cancer (ICD-9 154) | ||||
Non-cholecystectomycohort (N = 525) | 3 | 0.71 | 1(Reference) | 1(Reference) |
Cholecystectomy | ||||
Lapraroscopic cholecystectomy (N = 282) | 1 | 0.44 | 0.61(0.06, 5.87) | 0.42(0.04, 4.80) |
Non-lapraroscopic cholecystectomy (N = 243) | 0 | 0 | - | - |
Rate#, incidence rate, per 1,000 person-years; Crude HR *, relative hazard ratio; Adjusted HR†: multivariable analysis including age, sex, and comorbidities of hyperlipidemia, diabetes, liver cirrhosis, hypertension, COPD, stroke, CAD, and HCV