Table 1. Distribution of Ala147Thr genotypes by sex among cases and non-cases in studies included in the meta-analysis.
Included Study | GG Genotype | GA Genotype | AA Genotype | Minor Allele Frequency | ||||
---|---|---|---|---|---|---|---|---|
Cases | Noncases | Cases | Noncases | Cases | Noncases | Cases | Noncases | |
MALES | ||||||||
Martini et al. 2006 | 96 | 94 | 94 | 85 | 12 | 22 | 0.292 | 0.321 |
Tregouet et al. 2009 | 105 | 185 | 101 | 150 | 23 | 35 | 0.321 | 0.297 |
Steinbrugger et al. 2010 | 67 | 65 | 53 | 62 | 13 | 9 | 0.297 | 0.294 |
Antoni et al. 2011 | 234 | 174 | 238 | 143 | 50 | 31 | 0.324 | 0.295 |
Heit et al. 2012 | 332 | 322 | 323 | 305 | 90 | 63 | 0.338 | 0.312 |
de Hann et al. 2012 | 619 | 1020 | 584 | 925 | 120 | 222 | 0.311 | 0.316 |
Tokgoz et al. 2012 | 7 | 19 | 8 | 21 | 3 | 4 | 0.389 | 0.330 |
Orikaza et al. 2014 | 20 | 11 | 26 | 19 | 4 | 3 | 0.340 | 0.379 |
FEMALES | ||||||||
Martini et al. 2006 | 140 | 117 | 104 | 125 | 25 | 29 | 0.286 | 0.338 |
Tregouet et al. 2009 | 94 | 394 | 67 | 378 | 21 | 86 | 0.299 | 0.321 |
Steinbrugger et al. 2010 | 82 | 82 | 54 | 90 | 15 | 27 | 0.278 | 0.362 |
Antoni et al. 2011 | 476 | 354 | 421 | 334 | 123 | 74 | 0.327 | 0.316 |
Heit et al. 2012 | 365 | 250 | 312 | 345 | 81 | 74 | 0.313 | 0.368 |
de Hann et al. 2012 | 704 | 1140 | 634 | 1043 | 149 | 249 | 0.313 | 0.317 |
Tokgoz et al. 2012 | 21 | 21 | 15 | 27 | 5 | 8 | 0.305 | 0.384 |
Orikaza et al. 2014 | 63 | 51 | 73 | 46 | 14 | 13 | 0.303 | 0.327 |