Table 2.
Disease classification (as per Montreal criteria) | |
---|---|
Age at diagnosis | |
A1 16 y or below | 5 (10%) |
A2 17–40 y | 34 (71%) |
A3 above 40 y | 9 (19%) |
Location | |
L1 ileal | 11 (23%) |
L2 ileocolonic | 17 (35%) |
L3 colonic | 20 (42%) |
L4 upper GI | 3 (6%) |
P perianal | 11 (23%) |
Behavior | |
B1 non-stricturing/penetrating | 29 (60%) |
B2 stricturing | 11 (23%) |
B3 penetrating | 8 (17%) |
Median duration since CD diagnosis (range) y | 14 (1–46) |
Active disease, as per: | |
Disease activity score | |
HBI ≥ 5 | 20 (42%) |
Median HBI (range) | 4 (1–18) |
Intestinal inflammation | |
Faecal calprotectin ≥ 150 µg/g | 25 (52%) |
Median calprotectin (range) µg/g | 255 (30–1800) |
Systemic inflammation | |
CRP ≥ 5 mg/l | 13 (27%) |
Median CRP (range) mg/l | 2.4 (0.4–45) |
Low iron status (serum ferritin ≤ 30 g/l) | 8 (17%) |
Prior bowel resection for CD | 19 (40%) |
Documented psychological comorbidity | 15 (31%) |
Current therapy | |
Corticosteroid use | 6 (13%) |
Immunomodulator use | 26 (54%) |
Anti-TNF use | 12 (25%) |
Smoking status | |
Current smoker | 8 (17%) |
Ex-smoker | 19 (40%) |
Never smoked | 21 (43%) |
CD: Crohn’s disease; y: years; TNF: tumour necrosis factor; GI: gastrointestinal; HBI: Harvey–Bradshaw Index; CRP: C-reactive protein.