Regional brain activation (red) and deactivation (blue) in each group during the 2-back task compared to 0-back condition. Voxel-wise probability was thresholded at P<0.01 and cluster-wise probability was thresholded at <1 false positives. Z-coordinates refer to the axial level in MNI space. All groups displayed activation in the lateral prefrontal and posterior parietal cortex. Abbreviations: MZ, monozygotic; DZ, dizygotic; Sibl, siblings; Cc, concordant; Dc, discordant; L, left; R, right.