Figure 3.

Effects of bipolar status on activation during the 2-back task in the three groups that did not include patients with BPD (MZ discordant unaffected, DZ & Siblings discordant unaffected, and all control twins). The groups showed significant differences in activation in the temporal, orbitofrontal, and anterior cingulate cortex. Box-plots indicate extracted parameter estimates in each region. Voxel-wise probability was thresholded at p<0.01 and cluster-wise probability at <1 false positive. Abbreviations: L, left; R, right.