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. 2017 May 26;7:2465. doi: 10.1038/s41598-017-02496-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of CGs on the APs of Zebrafish larva. Effects of BF, CBG, Oua and PEA (all at 100 µM) on the APs, controlled by digoxin, were analysed in day-3 Zebrafish larva. (A, B and C) Bar-graphs show the effects of various CGs on heart rates, APD and APDc, respectively. (D) Representative waveforms of APs recorded. The dashed lines indicate the representative APDs. *p < 0.05, ^‡ p < 0.001, vs. control; ^‡ p < 0.001, vs. BF or CBG (One-Way ANOVA). Data are presented as mean ± SD.