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. 2017 May 1;7(5):1136–1150.

Figure 2.

Figure 2

MiR-146b-5p promotes cell growth, inhibits apoptosis, enhances invasion and glycolysis in CRC cells. A. MiR-146b-5p mimic significantly enhances expression level of miR-146b-5p. B. Ectopic overexpression of miR-146b-5p promotes CRC cell growth, as demonstrated by CCK-8 assay. C. Ectopic overexpression of miR-146b-5p enhances long term cell proliferation, as colonigenic assay. D. Overexpression of miR-146b-5p is associated with less apoptosis in CRC cells. E. MiR-146b-5p enhances in cell invasion. F. MiR-146b-5p mimic transfection significantly changes the expression levels of marker molecules for apoptosis and invasion. G. MiR-146b-5p overexpression enhances the glucose consumption of CRC cells. H. MiR-146b-5p overexpression promotes the production of lactate. **P<0.01.