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. 2017 May 1;7(5):1136–1150.

Figure 3.

Figure 3

Anti-miR-146b-5p inhibited cell growth, induces apoptosis, suppresses invasion and glycolysis of CRC cells. A. Knockdown of miR-146b-5p significantly decreases the expression of miR-146b-5p in CRC cells. B. Knockdown of miR-146b-5p inhibits cell growth, as demonstrated by CCK-8 assay. C. Knockdown of miR-146b-5p suppresses the long-term proliferation of CRC cells, as demonstrated by colonigenic assay. D. Anti-miR-146b-5p promotes cell apoptosis. E. Anti-miR-146b-5p is associated with significantly less invasion of CRC cells. F. Anti-miR-146b-5p regulated the expression of marker molecules involved in apoptosis and invasion. G. Anti-miR-146b-5p transfection leads to decrease in glucose consumption. H. Knockdown of miR-146b-5p results in less production of lactate. **P<0.01.