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AKT3 downregulation mimicked the inhibitory effect of miR-338-3p overexpression in thyroid cancer cells. (A, B) AKT3 mRNA (A) and protein (B) levels were determined in TPC-1 cells transfected with si-AKT3 or si-NC. GAPDH was used as an internal control. (C-F) Cell proliferation, colony formation, migration, and invasion were analyzed in TPC-1 cells transfected with si-AKT3 or si-NC. *P < 0.05, **P < 0.01.
