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AKT3 overexpression rescues the miR-338-3p-mediated inhibitory effect on thyroid cancer cells. (A, B) AKT3 mRNA (A) and protein (B) expression levels were analyzed in TPC-1 cells transfected with miR-338-3p or miR-NC, with/without the AKT3-overexpressing plasmid. (C-F) Cell proliferation, colony formation, migration, and invasion were analyzed in TPC-1 cells transfected with miR-338-3p or miR-NC, with/without the AKT3-overexpressing plasmid. *P < 0.05, **P < 0.01.
