Figure 2.

OSC improved the viability and reduced the LDH release in OGD/R-treated BV-2 cells. A and C. BV-2 cells were exposed to OGD for 3 h followed by 24 h of reoxygenation. OSC (1, 3, and 5 μM) was added to the medium immediately after the OGD phase. A. Cell viability was measured by MTT assay. C. LDH release was assessed. B and D. BV-2 cells were exposed to OGD for 3 h followed by 0, 12, 24, and 48 h of reoxygenation. OSC (3 μM) was added to the medium immediately after the OGD phase. B. Cell viability was measured by MTT assay. D. LDH release was assessed. Data are derived from three independent experiments and expressed as means ± SD. *P < 0.05 vs. control (Ctrl) group; #P < 0.05 vs. OGD/R group.