Table 2.
Association of clinicopathological parameters with CIP2A and E2F1 expression
| CIP2A | E2F1 | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| (-) | (+) | (-) | (+) | |||
| Age (years) | P=0.188 | P=0.239 | ||||
| ≤40 | 52 | 10 | 53 | 9 | ||
| >40 | 94 | 28 | 110 | 12 | ||
| Tumor size, cm | P<0.001* | P=0.388 | ||||
| <4 | 107 | 16 | 110 | 13 | ||
| ≥4 | 39 | 22 | 53 | 8 | ||
| LN metastasis | P=0.003* | P=0.573 | ||||
| No | 119 | 22 | 125 | 16 | ||
| Yes | 27 | 16 | 38 | 5 | ||
| Differentiation grade | P=0.267 | P=0.303 | ||||
| Well to moderate | 70 | 21 | 79 | 12 | ||
| Poor | 76 | 17 | 84 | 9 | ||
| FIGO staging (range) | P=0.270 | P=0.342 | ||||
| I | 127 | 31 | 141 | 17 | ||
| II to IV | 19 | 7 | 22 | 4 | ||
| Distant metastasis | P=0.571 | P=0.570 | ||||
| No | 133 | 35 | 149 | 19 | ||
| Yes | 13 | 3 | 14 | 2 | ||
| Depth of invasion | P=0.005* | P=0.402 | ||||
| <1/2 | 41 | 3 | 40 | 4 | ||
| ≥ 1/2 | 105 | 35 | 123 | 17 | ||
| Histotype | P=0.583 | P=0.162 | ||||
| SCC | 135 | 35 | 149 | 21 | ||
| AC | 11 | 3 | 14 | 0 | ||
Note: LN, lymph node; FIGO staging, the International Federation of Gynecology and Obstetrics Staging; SCC, squamous cell carcinoma; AC, adenocarcinoma.
*
Indicates statistical significance.