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. 2017 May 15;9(5):2520–2534.

Figure 1.

Figure 1

Histological analysis of the hearts. A. Myocardium from the four groups with hematoxylin and eosin staining (magnification, 1 = ×100, 2 = ×400; bar = 100 µm). Green arrows indicate coronary arterioles (vessels <100 µm in diameter). Two treatment groups exhibited a lower incidence of thromboembolism, compared with the other groups. B. Myocardium from the four groups with Heidenhain’s hematoxylin staining (magnification, 1 = ×100, 2 = ×400; bar = 100 µm). Red arrows indicate early myocardial ischemia. Both PGE1(H) and PGE1(L) groups exhibited a lower incidence of early myocardial ischemia than did the CME group. C. Transmission electron microscopy of coronary arterioles and mitochondria. En, endothelium; Er, erythrocyte; F, fibrin; and M, mitochondria (magnification ×10000 for a and ×25000 for b; bar = 2 µm for a and 1 µm for b). These pathological changes in the CME group were partially inhibited by PGE1.