iNOS plays a critical role in inflammation and oxidative stress processes in severely burned rats. A: The relative gene activity of iNOS, eNOS, and nNOS were assayed after treatment with L-NAME. B: The content of NO was measured after treatment with L-NAME. C: Inflammatory factors (Ifs) were measured after treatment with L-NAME. D: Oxidative stress factors (OSFs) were measured after treatment with L-NAME. Data are presented as the mean ± standard error of measurement (SEM) (n = 3) with *P < 0.05, **P < 0.01, or ***P < 0.001, analyzed by two-way ANOVA.