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Administration of hASCs reduced the inflammatory responses in CIA. A: IL-1β, TNF-α, IFN-γ, and IL-6 were significantly reduced in dex-treated mice and in all hASC-treated mice. IL-10 levels were significantly increased in all hASC-treated, but not index-treated mice. B: Serum concentrations of anti-CII IgG and anti-CII IgG2a antibodies were significantly decreased after treatment with hASCs. All data are expressed as Means ± SD, **P<0.01, *P<0.05.
