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. 2017 Apr 22;174(12):1797–1809. doi: 10.1111/bph.13776

Figure 1.

Figure 1

3D representation of a pellet (A) with its 2D axisymmetric schematization (B). Ω0 represents the inert core (Cellets) with fixed radius R0. ΩA represents the solid drug layer (drug and HPMC) with the time‐dependent outer radius RA(t). ΩB represents the dissolved drug layer (drug, HPMC and water) with time‐dependent outer radius RB(t). ΩC represents the polymeric film layer (Surelease, drug and water) with the time‐dependent outer radius RC(t). ΩD represents the dissolution medium (drug and water) in which the pellet is immersed.