TABLE 2.
Comparison of H15 HA with group 1 and other group 2 subtypes
| HA strain | PDB code | RMSD values of C-α atoms (Å)a |
RBS subdomainb | Alignment score (%)c | ||
|---|---|---|---|---|---|---|
| Monomer | HA1 | HA2 | ||||
| H3N2_A/Hong_Kong/1/1968 | 4FNK | 1.3 (462) | 1.4 (301) | 0.6 (160) | 0.9 (126) | 47 |
| H14N6_A/Mallard/Gurjev/244/1982 | 3EYK | 1.4 (484) | 1.3 (313) | 0.6 (168) | 0.9 (130) | 49 |
| H7N9_A/Shanghai/02/2013 | 4N5J | 1.1 (486) | 0.5 (316) | 0.4 (168) | 0.4 (149) | 79 |
| H10N8_A/Jiangxi/IPB13a/2013 | 4XQ5 | 1.7 (486) | 0.7 (316) | 0.6 (168) | 0.6 (145) | 65 |
| H1N1_A/California/04/2009 | 3AL4 | 2.5 (428) | 1.9 (266) | 1.0 (127) | 0.6 (109) | 40 |
| H2N2_A/Japan/305/1957 | 3KU5 | 2.7 (424) | 1.8 (264) | 1.0 (140) | 0.6 (100) | 41 |
| H5N1_A/Vietnam/4/2003 | 2FK0 | 2.8 (415) | 2.0 (244) | 0.9 (136) | 0.7 (109) | 41 |
a
The numbers in parentheses are the numbers of residues included in the comparison.
b
The receptor-binding subdomain (RBS subdomain) is defined as residues 117 to 265 of the HA1 subunit (H3 numbering). The number in parentheses are the number of residues.
c
Calculated for the HA sequence (Fig. S1) using Clustal W2 (ENBL-EBI) (63).