TABLE 1.

siRNAs used in this study

siRNA no.	Name	Target sequence (5′–3′) or product name	Company	Knockdown efficiencya
1	siGOLM1	AACAAGCTGTACCAGGACGAA	Gene Design	0.02
2	siSNAP25	GTTGGATGAGCAAGGCGAA	Gene Design	0.37
3	siSNAP25#2	GGGTAACAAATGATGCCCG	Gene Design	0.51
4	siNR2F6	CGGUGCUGGGCAUCGACAATT	Gene Design	0.24
5	siADORA2B	GUAUCUAGCUAAUAUGUAUUU	Gene Design	0.50
6	siTMUB1	CCTCAATGATTCAGAGCAG	Gene Design	0.09
7	siPDK4	GGACGTAAGAGATTCTCAT	Gene Design	0.23
8	siSLC7A11	AAATGCCCAGATATGCATCGT	Gene Design	0.59
9	siTXN2#2	GGATGGACCTGACTTTCAA	Gene Design	0.04
10	siSNAP23	CGCATAACTAATGATGCCA	Gene Design
10	siSTX4	GCAACTCAATGCAGTCCGATT	Gene Design
10	siANKRD40	Hs_ANKRD40_1 FlexiTube siRNA	Qiagen	0.13
11	siGPAM	Hs_GPAM_6 FlexiTube siRNA	Qiagen	0.15
12	siTXN2	Hs_TXN2_2 FlexiTube siRNA	Qiagen	0.02
13	siTMBIM6	Hs_TEGT_6 FlexiTube siRNA	Qiagen	0.01
14	siPAPSS2	Hs_PAPSS2_1 FlexiTube siRNA	Qiagen	0.06
15	siSFXN2	Hs_SFXN2_6 FlexiTube siRNA	Qiagen	0.17
16	siGOLM1#2	Hs_GOLPH2_5 FlexiTube siRNA	Qiagen	0.09

^aDetermined in HeLa cells following transfection with the indicated siRNA at 50 nM. mRNA levels in siControl-transfected cells were normalized to 1.