TABLE 4.
Fibrosis gene expression in EGFR(DSK5) micea
| Gene symbol | Relative expression in: |
|||
|---|---|---|---|---|
| WT mice |
EGFR(DSK5) mice |
|||
| Day 2 | Day 9 | Day 2 | Day 9 | |
| Icam1 | 1.5488509 | 1.149609225 | 1.855424964 | 1.596337223 |
| Il1a | 3.288089931 | 1.360019535 | 3.733819792 | 1.268028953 |
| Lbp | 2.114673337 | 1.354119802 | 2.465446331 | 1.651924068 |
| Tnfrsf1b | 2.141017245 | 1.571891356 | 2.567532492 | 1.604735456 |
| Csf1 | 2.614548822 | 1.074479563 | 3.017590801 | 1.192906217 |
| Nfkb2 | 2.23092147 | 1.477704937 | 2.553398864 | 1.689226187 |
| Pgf | 1.297801029 | 0.922719994 | 1.559461165 | 1.21046921 |
| Igf1 | 1.729322597 | 1.466890553 | 1.183183704 | 1.79667449 |
| Cd14 | 2.273261608 | 1.63241027 | 2.797950968 | 2.300910993 |
| Vcam1 | 3.872032809 | 2.275403928 | 3.813511014 | 2.692949764 |
| Il10ra | 2.636166587 | 1.738759567 | 3.434222512 | 1.570842461 |
| Fn1 | 0.965818404 | 1.042014427 | 0.876528132 | 1.518873118 |
| Il1b | 2.976961766 | 1.462845702 | 3.944742834 | 1.255383575 |
| Mmp13 | 1.446779091 | 0.858945741 | 1.421877303 | 1.09470478 |
| Tnf | 3.893191375 | 1.903284029 | 4.91475242 | 2.02484063 |
| Ccl5 | 5.896558456 | 4.5596542 | 7.093102609 | 4.125477387 |
| Ccr5 | 2.396554655 | 2.530801276 | 3.197457529 | 2.551879222 |
| Il1r2 | 4.379792999 | 0.976313838 | 6.631179804 | 1.364979541 |
| Cxcl3 | 2.090822527 | 1.715251649 | 2.235176947 | 1.41874425 |
| Col3a1 | 2.153502052 | 1.984695884 | 1.9827388 | 3.452700619 |
| Timp1 | 10.10057928 | 2.157322024 | 13.36329825 | 7.326072203 |
| Ccl2 | 22.06441303 | 2.780114177 | 24.08748908 | 4.780781876 |
| Il6 | 23.77820489 | 1.885805582 | 30.85256895 | 2.526872922 |
| Ifng | 1.312446528 | 1.17875933 | 1.763109244 | 1.316881769 |
a
The gene expression values were used to create the heat maps in Fig. 5B.