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. 2017 May 26;91(12):e00487-17. doi: 10.1128/JVI.00487-17

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FIG 1 — Multiple-sequence alignment of motif F1 of viral RdRp. Part of the multiple-sequence alignment of RdRp of chikungunya virus (ACY09947.1), enteroviruses (coxsackievirus A21 [ABM54541.1], coxsackievirus B3 [AAA74400.1], poliovirus type 1 [AAP37265.1], enterovirus D68 [AAR98503.1], and human rhinovirus B14 [NP_740525.1]), flaviviruses (Zika virus [AMO03410.1] and Japanese encephalitis virus [ABU94628.1]), murine norovirus (AEY83582.1), and hepatitis C virus (CAB46913.1) was generated using the PROMALS server (http://prodata.swmed.edu/promals/promals.php). Motif F1 of the RdRp is indicated by a black box, and the residues corresponding to K291 in CHIKV are highlighted in yellow.