Table 1.
Demographic and clinicopathological factors in patients with and without sarcopenia who underwent pancreaticoduodenectomy
| All patients (n = 219) |
Non-sarcopenia (n = 164) |
Sarcopenia (n = 55) |
P-value | |
|---|---|---|---|---|
| Demographic variables | ||||
| Sex (men) | 143 (65.3) | 107 (65.2) | 36 (65.5) | 0.98 |
| Age (years) | 65.9 (11.7) | 65.1 (12.4) | 68.2 (9.2) | 0.18 |
| BMI (kg/m2) | 21.9 (3.3) | 22.0 (3.4) | 21.7 (3.0) | 0.67 |
| ASA physical status | ||||
| 1–2/3 | 203/16 | 154/10 | 49/6 | 0.25 |
| Laboratory value | ||||
| Albumin (g/dL) | 4.0 (0.5) | 4.1 (0.4) | 3.9 (0.6) | 0.006 |
| Total lymphocyte (/mm3) | 1642 (554) | 1665 (561) | 1572 (521) | 0.30 |
| Child–Pugh score | ||||
| A/B | 205/14 | 155/9 | 50/5 | 0.36 |
| Comorbidities | ||||
| Hypertension | 89 (40.6) | 68 (41.5) | 21 (38.2) | 0.67 |
| Diabetes | 64 (29.2) | 43 (26.2) | 21 (38.2) | 0.10 |
| Etiology of the disease | ||||
| Pancreatic adenocarcinoma | 86 (39.3) | 61 (37.2) | 25 (45.5) | 0.31 |
| Bile duct carcinoma | 27 (12.3) | 20 (12.2) | 7 (12.7) | |
| Ampullary adenocarcinoma | 28 (12.8) | 18 (11.0) | 10 (18.2) | |
| Duodenal adenocarcinoma | 10 (4.6) | 9 (5.5) | 1 (1.8) | |
| IPMN | 32 (14.6) | 26 (15.9) | 6 (10.9) | |
| Others | 36 (16.4) | 30 (18.3) | 6 (10.9) | |
| Preoperative biliary drainage | 101 (46.1) | 68 (41.5) | 33 (60.0) | 0.02 |
| Intraoperative factor | ||||
| Operative time (min) | 448 (93) | 445 (93) | 454 (94) | 0.64 |
| Blood loss (mL) | 563 (486) | 543 (443) | 624 (596) | 0.96 |
| Vascular reconstruction | 50 (22.8) | 37 (22.6) | 13 (23.6) | 0.87 |
| Soft pancreatic texture | 133 (60.7) | 101 (61.6) | 32 (58.2) | 0.66 |
| Normal pancreatic duct (< 3 mm) | 87 (39.7) | 69 (42.1) | 18 (32.7) | 0.22 |
Data are presented as numbers (percentages) or means (± standard deviation).
BMI body mass index, ASA American Society of Anesthesiologists, IPMN intraductal papillary mucinous neoplasm