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. 2017 May 26;14:98. doi: 10.1186/s12985-017-0766-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Comparison of the genome organizations of AcCoV-JC34, LRNV, HKU2, FCoV, 229E, MHV, HKU24, and WIV1. Predicted ORFs and 5 conserved domains are indicted by the boxes. Abbreviations: 3CL, 3C-like protease; E, envelope; HE, hemagglutinin-esterase; Hel, helicase; M, membrane; N, nucleocapsid; PL1pro and PL2P, papain-like proteases 1 and 2; RdRp, RNA-dependent RNA polymerase; S, spike