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. 2017 May 26;12:14. doi: 10.1186/s13015-017-0106-z

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — a Illustration of the score of a candidate median gene. b Gene similarity graph of three genomes G, H, and I. Colored components indicate candidate median genes $m_{1} = (g_{1}, h_{1}, i_{2})$ , $m_{2} = (g_{2}, h_{2}, i_{1})$ , $m_{3} = (g_{3}, h_{3}, i_{2})$ , and $m_{4} = (g_{4}, h_{3}, i_{3})$ . Median gene pairs $m_{1}, m_{3}$ and $m_{3}, m_{4}$ are conflicting