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Cases classified as having ‘severe’ pathology display a large variation in pathology load. a Hyperphosphorylated tau (HP-T) load in the entorhinal cortex in cases classified as neuritic Braak stage VI. b β amyloid load in the frontal cortex in cases classified as Thal phase 5 and c α-Synuclein (α-syn) load in the cingulate cortex in Lewy body disease (LBD) cases that are classified as McKeith neocortical LBD
