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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Pattern Recognit. 2016 Sep 22;63:710–718. doi: 10.1016/j.patcog.2016.09.031

Figure 1.

Figure 1

In this maximum intensity projection of 3-D fluorescence microscopy image of murine cranial tissue, miscellaneous imaging artifacts are visible: uneven illumination (upper vs. lower parts), non-homogenous intensity distribution inside the vessels (visible in the larger vessels located at top right corner), low SNR regions (lower areas), high spatial density or closeness of vessels (majorly in the center-upper parts), reduced contrast at edges (visible as blurs mostly for the central vessels), broken or faint vessels (lower vessels), and low frequency background variations caused by scattered light (at higher density regions).