Table 2. Risk factors for current AR in preschool children.
Risk factors | OR (95% CI) | P value | aOR* (95% CI) | P value |
---|---|---|---|---|
Genetic factors | ||||
Parental asthma | 3.22 (1.71–6.07) | <0.001 | 2.10 (1.08–4.08) | 0.028 |
Parental AR | 2.88 (2.01–4.14) | <0.001 | 2.25 (0.92–5.52) | 0.077 |
Parental AD | 1.49 (0.91–2.43) | 0.115 | 0.93 (0.54–1.61) | 0.800 |
Past history | ||||
Past history of asthma diagnosis | 3.44 (2.10–5.63) | <0.001 | 2.96 (1.73–5.08) | <0.001 |
Wheezing, last 12 months | 1.89 (1.13–3.16) | 0.015 | 2.09 (1.21–3.59) | 0.008 |
Past history of AD diagnosis | 1.74 (1.23–2.47) | 0.002 | 1.61 (1.11–2.34) | 0.012 |
History of bronchiolitis before 2 years of age | 1.39 (0.91–2.12) | 0.132 | 1.18 (0.74–1.89) | 0.479 |
Breast milk feeding >6 months | 1.27 (0.84–1.95) | 0.262 | 1.24 (0.80–1.94) | 0.338 |
Use of antibiotics in infancy (>3 days) | 1.95 (1.36–2.80) | <0.001 | 1.97 (1.33–2.90) | <0.001 |
Cesarean-section delivery | 1.35 (0.95–1.92) | 0.100 | 1.37 (0.94–2.00) | 0.099 |
Environmental tobacco smoking | 1.09 (0.77–1.53) | 0.127 | 1.15 (0.79–1.67) | 0.460 |
Current pet ownership | 0.63 (0.19–2.12) | 0.451 | 0.66 (0.19–2.29) | 0.508 |
Pet ownership in infancy | 0.85 (0.37–1.94) | 0.323 | 0.80 (0.34–1.86) | 0.600 |
Dog ownership in infancy | 0.96 (0.42–2.21) | 0.928 | 0.90 (0.38–2.12) | 0.810 |
Cat ownership in infancy | 1.17 (0.13–10.51) | 0.891 | 1.00 (0.11–9.30) | 0.996 |
Day care attendance before 1-year-old | 0.84 (0.48–1.48) | 0.551 | 0.97 (0.53–1.76) | 0.908 |
Having an older sibling | 0.56 (0.39–0.79) | <0.001 | 0.52 (0.35–0.75) | 0.001 |
Having a younger sibling | 1.09 (0.76–1.57) | 0.633 | 1.11 (0.77–1.64) | 0.561 |
History of remodeling, currently | 0.92 (0.57–1.48) | 0.736 | 0.82 (0.48–1.39) | 0.452 |
Indoor mold exposure during infancy | 1.69 (1.18–2.40) | 0.004 | 1.67 (1.15–2.43) | 0.007 |
Indoor mold exposure during previous last 12 months | 1.18 (0.84–1.67) | 0.347 | 1.09 (0.75–1.58) | 0.646 |
AR, allergic rhinitis; OR, odds ratio; aOR, adjusted odds ratio; CI, confidence interval; AD, atopic dermatitis; BMI, body mass index.
*Adjusted by age, sex, BMI, parental history of allergic diseases, and maternal education levels.