Table 1.
Subject demographics.
| Subject | Sex | Age, y | Time since stroke, mo | Type of stroke | Lesion distribution | Lesion volume (cm3) | WAB-AQ | Optimal montage | Number of nouns (baseline) | Number of nouns (2 weeks) | Number of nouns (2 months) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| REAL tDCS | |||||||||||
| R1 | M | 65 | 27 | Ischemic | Left MCA | ~ | 29.1 | Anode F3 | 0 | 0 | |
| S1/R2 | M | 53 | 67 | Ischemic | Fronto-parietal cortical and subcortical, including internal capsule, basal ganglia, anterior IFG | 165.49 | 87.8 | Anode F3 | 14 | 20 | 14 |
| R3 | M | 54 | 8 | Ischemic | Large fronto-temporo-parietal lesion involving STG, parietal cortex, IFG, and subcortical white matter Caudate and thalamus spared | 271.02 | 38.9 | Cathode F3 | 4 | 8 | 1 |
| R4 | M | 76 | 100 | Ischemic | Fronto-temporo-parietal subcortical, including corona radiata Internal capsule, deep gray structures, and IFG spared | 145.94 | 69.6 | Cathode F3 | 27 | 27 | 17 |
| S2/R5 | M | 61 | 28 | Hemorrhagic | Fronto-parietal lesion involving sensorimotor and superior parietal cortices, and subcortical white matter IFG, inferior parietal gyrus, temporal cortex, deep gray structures, and thalamus spared | 134.04 | 83.0 | Cathode F4 | 30 | 20 | 23 |
| S4/R6 | M | 67 | 10 | Ischemic | Fronto-parietal lesion involving supramarginal gyrus, temporo-parietal-occipital junction, insula, IFG, and underlying subcortical white matter Basal ganglia and thalamus spared | 89.8 | 69.5 | Cathode F3 | 22 | 19 | 19 |
| S5/R7 | F | 84 | 26 | Ischemic | Left MCA | ~ | 78.1 | Anode F3 | 8 | 8 | 9 |
| S6/R8 | F | 50 | 116 | Ischemic | Left MCA | ~ | 78.7 | Anode F4 | 14 | 15 | 15 |
| Mean (StdDev) | 62.0 (±1 0.8) | 50.5 (± 41.2) | 15 (± 10.7) | 17 (± 6.9) | 12 (± 8.3) | ||||||
| SHAM tDCS | |||||||||||
| S1/R2 | M | 53 | 67 | Ischemic | 14 | 12 | 15 | ||||
| S2/R5 | M | 61 | 28 | Hemorrhagic | 30 | 22 | 23 | ||||
| S3 | M | 61 | 12 | Ischemic | Large fronto-temporo-parietal lesion involving STG, parietal cortex, left IFG and subcortical white matter Deep gray structures and thalamus spared | 266.29 | 23.2 | 1 | 0 | 0 | |
| S4/R6 | M | 67 | 10 | Ischemic | 22 | 19 | 15 | ||||
| S5/R7 | F | 84 | 26 | Ischemic | 8 | 5 | 10 | ||||
| S6/R8 | F | 50 | 116 | Ischemic | 14 | 12 | 17 | ||||
| Mean (StdDev) | 57.3 (± 4.6) | 35.7 (±2 8.3) | 15 (± 10.1) | 12 (± 8.3) | 13 (± 7.8) | ||||||
MCA, Middle cerebral artery; IFG, Inferior frontal gyrus; STG, Superior temporal gyrus; SD, Standard deviation. Of note, structural images were reviewed during subject screening and enrolment but were not available during data analysis or results reporting (~). Additionally, areas in gray under the sham tDCS section represent previously stated demographics for the same subjects in the real tDCS.